Giant Cell Arteritis

Giant cell arteritis is an inflammatory condition of the medium and large arteries with symptoms concentrated in the head and neck.

About Giant Cell Arteritis

Giant cell arteritis is a form of vasculitis (inflammatory vessel disease) that affects medium and large arteries. It is the most common form of vasculitis in adults over the age of 50. The condition most often affects the temporal arteries, large vessels which supply blood to your head and neck. For this reason, many symptoms of the disease are localized to this region.

Symptoms of Giant Cell Arteritis

The onset of giant cell arteritis symptoms tends to span weeks or months. In less common instances, symptom onset is more abrupt.

Symptoms of giant cell arteritis may include:

  • Fatigue
  • Fever
  • Headache
  • Jaw pain
  • Loss of vision
  • Headache
  • Scalp tenderness
  • Stroke

Risk Factors for Giant Cell Arteritis

Researchers have identified several risk factors that may increase your likelihood of developing giant cell arteritis.

Risk factors for giant cell arteritis may include:

  • Age: The condition typically affects people over the age of 50.
  • Family history: Giant cell arteritis is most common in individuals of Scandinavian descent. Individuals with the HLA-DRB1*04 gene are more likely to develop the condition.
  • Sex: The condition is more common in female patients.

Treating Giant Cell Arteritis at UT Medicine 

Like all forms of vasculitis, corticosteroids like prednisone can be used to address the inflammation associated with giant cell arteritis. Your physician may also use a drug called tocilizumab which is thought to prevent the immune system from attacking healthy tissue. Throughout the course of your treatment, you can expect compassionate care from each provider in the clinic.

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